Causes and Risks: any of the following

• amphotericin B
• calcium undecylenate
• ciclopirox olamine
• clioquinol (iodochlorhydroxyquin)
• clotrimazole
• gentian violet (methylrosaniline chloride, crystal violet)
• haloprogin
• ketoconazole
• miconazole nitrate
• naftifine HCl
• nystatin
• oxiconazole nitrate
• sulconazole nitrate
• terbinafine HCl
• tolnaftate
• triacetin (glyceryl triacetate)
• undecylenic acid
• zinc undecylenate

Where Found:

• amphotericin B (Fungizone)
• ciclopirox olamine (Loprox)
• clioquinol [iodochlorhydroxyquin] (Vioform)
• clotrimazole (Lotrimin, Mycelex)
• gentian violet [methylrosaniline chloride, crystal violet]
• haloprogin (Halotex)
• ketoconazole (Nizoral)
• miconazole nitrate (Micatin, Monistat-Derm)
• naftifine HCl (Naftin)
• nystatin (Mycostatin, Nilstat, Nystex)
• oxiconazole nitrate (Oxistat)
• sulconazole nitrate (Excelderm)
• terbinafine HCl (Lamisil)
• tolnaftate (Genaspor, NP-27, Tinactin, Ting, Aftate, Absorbine Antifungal, Absorbine Jock Itch, Quinsana Plus, Zeasorb-AF)
• triacetin [glyceryl triacetate] (Fungoid, Ony-Clear Nail)
• undecylenic acid or derivatives [calcium undecylenate,

Symptoms: Symptoms may result from base of product. Creams and ointments may cause vomiting and diarrhea, while power-based products that contain talc can cause pneumonia.
amphotericin B

• body as a whole
  • fever
  • chills
• gastrointestinal
  • loss of appetite
  • abdominal distention
  • bloody diarrhea
• mild kidney damage

• no information

• no information

• skin
  • blistering of skin

• body as a whole
  • exposed skin and mucus membranes will turn purple
  • death (rare)
  • dizziness (rare)
• respiratory
  • stop breathing (rare)
  • shortness of breath (rare)
• eyes, ears, nose, and throat
  • sores in throat may develop
  • eye damage may be seen following eye exposure
• gastrointestinal
  • nausea and/or vomiting
  • abdominal pain
• heart and blood vessels
  • low blood pressure

• skin
  • irritation
  • burning

• no information

• rapid heartbeat
• confusion (from IV administration only)

• skin rash, usually allergic

• skin
  • rash, usually allergic
• gastrointestinal
  • nausea and/or vomiting
  • diarrhea

• no information

• no information

• no information

• skin
  • mild irritation, usually allergic in nature

• no information

• body as a whole
  • fever
  • headache
• gastrointestinal
  • nausea, vomiting

Home Treatment: Call Poison Control.

If instructed to induce emesis (vomiting), the standard procedure is as follows:

Give the usual dose of ipecac syrup: 15 milliliters (ml) or 1 TABLEspoonful for children and 30 ml (2 TABLEspoonsful) for an adult. Follow with 1/2 glass or 4 ounces (oz.) of water for children or 8 to 12 oz. of water for adults. Repeat 1 more time in 1/2 hour if emesis has not occurred.

Before Calling Emergency: Determine the following information:

• the patient’s age, weight, and condition
• the name of the product (ingredients and strengths if known)
• the time it was swallowed
• the amount swallowed

Call Poison Control: They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What To Expect: Some or all of the following procedures may be performed:

• monitor vital signs
• treatment of symptoms

The prognosis (probable outcome) is likely to be good, depending on the amount ingested. Most of these agents are of low toxicity. Only skin irritation or stomach upset are expected. Gentain violet is slightly more irritating.